Enzymes drive nearly every process in a cell including metabolism, transcription of genes, and replication of DNA, among others. Enzymology is the study of how enzymes catalyze reactions, how such catalysis is regulated, how enzymes evolve and function and how enzymes can be inhibited to develop therapeutics. Enzymology is a multi-disciplinary science that includes molecular biology, kinetic analysis, structural biology and computational biology. The CPSB program provides an outstanding opportunity for graduate students to engage in the study of enzymes using advanced spectroscopy methods in addition to core facilities for protein purification, X-ray crystallography, cryo-electron microscopy. Finally, the Center for Drug Discovery facilitates the discovery of small molecule inhibitors of enzymes.