Fabio Stossi, Ph.D.
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Fabio Stossi, Ph.D.
Associate Professor
Positions
- Associate Professor
-
Mol and Cell Biology-Mancini
Baylor College of Medicine
Houston, TX US
Websites
Selected Publications
- Zhou HB, Carlson KE, Stossi F, Katzenellenbogen BS, Katzenellenbogen JA "Analogs of methyl-piperidinopyrazole (MPP): antiestrogens with estrogen receptor alpha selective activity.." Bioorg. Med. Chem. Lett.. 2009 January 1; 19 (1): 108-10. Pubmed PMID: 19014882
- Waibel M, De Angelis M, Stossi F, Kieser KJ, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA "Bibenzyl- and stilbene-core compounds with non-polar linker atom substituents as selective ligands for estrogen receptor beta.." Eur J Med Chem. 2009 September ; 44 (9): 3412-24. Pubmed PMID: 19286283
- Bolt MJ, Stossi F, Newberg JY, Orjalo A, Johansson HE, Mancini MA "Coactivators enable glucocorticoid receptor recruitment to fine-tune estrogen receptor transcriptional responses.." Nucleic Acids Res.. 2013 April 1; 41 (7): 4036-48. Pubmed PMID: 23444138
- Zhou HB, Nettles KW, Bruning JB, Kim Y, Joachimiak A, Sharma S, Carlson KE, Stossi F, Katzenellenbogen BS, Greene GL, Katzenellenbogen JA "Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands.." Chem. Biol.. 2007 June ; 14 (6): 659-69. Pubmed PMID: 17584613
- Stossi F, Madak-Erdogan Z, Katzenellenbogen BS "Estrogen receptor alpha represses transcription of early target genes via p300 and CtBP1.." Mol. Cell. Biol.. 2009 April ; 29 (7): 1749-59. Pubmed PMID: 19188451
- Stossi F, Likhite VS, Katzenellenbogen JA, Katzenellenbogen BS "Estrogen-occupied estrogen receptor represses cyclin G2 gene expression and recruits a repressor complex at the cyclin G2 promoter.." J. Biol. Chem.. 2006 June 16; 281 (24): 16272-8. Pubmed PMID: 16608856
- Maggi R, Cariboni A, Zaninetti R, Samara A, Stossi F, Pimpinelli F, Giacobini P, Consalez GG, Rugarli E, Piva F "Factors involved in the migration of neuroendocrine hypothalamic neurons.." Arch Ital Biol. 2005 September ; 143 (41337): 171-8. Pubmed PMID: 16097493
- Madak-Erdogan Z, Lupien M, Stossi F, Brown M, Katzenellenbogen BS "Genomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs.." Mol. Cell. Biol.. 2011 January ; 31 (1): 226-36. Pubmed PMID: 20956553
- De Angelis M, Stossi F, Carlson KA, Katzenellenbogen BS, Katzenellenbogen JA "Indazole estrogens: highly selective ligands for the estrogen receptor beta.." J. Med. Chem.. 2005 February 24; 48 (4): 1132-44. Pubmed PMID: 15715479
- De Angelis M, Stossi F, Waibel M, Katzenellenbogen BS, Katzenellenbogen JA "Isocoumarins as estrogen receptor beta selective ligands: Isomers of isoflavone phytoestrogens and their metabolites.." Bioorg. Med. Chem.. 2005 December 1; 13 (23): 6529-42. Pubmed PMID: 16099659
- Likhite VS, Stossi F, Kim K, Katzenellenbogen BS, Katzenellenbogen JA "Kinase-specific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity.." Mol. Endocrinol.. 2006 December ; 20 (12): 3120-32. Pubmed PMID: 16945990
- Stossi F, Madak-Erdogan Z, Katzenellenbogen BS "Macrophage-elicited loss of estrogen receptor-a in breast cancer cells via involvement of MAPK and c-Jun at the ESR1 genomic locus.." Oncogene. 2012 April 5; 31 (14): 1825-34. Pubmed PMID: 21860415
- Minutolo F, Bellini R, Bertini S, Carboni I, Lapucci A, Pistolesi L, Prota G, Rapposelli S, Solati F, Tuccinardi T, Martinelli A, Stossi F, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, Macchia M "Monoaryl-substituted salicylaldoximes as ligands for estrogen receptor beta.." J. Med. Chem.. 2008 March 13; 51 (5): 1344-51. Pubmed PMID: 18269232
- Waibel M, Kieser KJ, Carlson KE, Stossi F, Katzenellenbogen BS, Katzenellenbogen JA "Phenethyl pyridines with non-polar internal substituents as selective ligands for estrogen receptor beta.." Eur J Med Chem. 2009 September ; 44 (9): 3560-70. Pubmed PMID: 19394116
- Frasor J, Stossi F, Danes JM, Komm B, Lyttle CR, Katzenellenbogen BS "Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells.." Cancer Res.. 2004 February 15; 64 (4): 1522-33. Pubmed PMID: 14973112
- Zhou HB, Comninos JS, Stossi F, Katzenellenbogen BS, Katzenellenbogen JA "Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: estrogen antagonists of unusual structure.." J. Med. Chem.. 2005 November 17; 48 (23): 7261-74. Pubmed PMID: 16279785
- Stender JD, Stossi F, Funk CC, Charn TH, Barnett DH, Katzenellenbogen BS "The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells.." Mol. Endocrinol.. 2011 October ; 25 (10): 1699-709. Pubmed PMID: 21868451
- Stossi F, Barnett DH, Frasor J, Komm B, Lyttle CR, Katzenellenbogen BS "Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) alpha or ERbeta in human osteosarcoma cells: distinct and common target genes for these receptors.." Endocrinology. 2004 July ; 145 (7): 3473-86. Pubmed PMID: 15033914
- Marshall GM, Gherardi S, Xu N, Neiron Z, Trahair T, Scarlett CJ, Chang DK, Liu PY, Jankowski K, Iraci N, Haber M, Norris MD, Keating J, Sekyere E, Jonquieres G, Stossi F, Katzenellenbogen BS, Biankin AV, Perini G, Liu T "Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects.." Oncogene. 2010 November 4; 29 (44): 5957-68. Pubmed PMID: 20697349
- Cariboni A, Davidson K, Dozio E, Memi F, Schwarz Q, Stossi F, Parnavelas JG, Ruhrberg C "VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels.." Development. 2011 September ; 138 (17): 3723-33. Pubmed PMID: 21828096
- Lin CY, Vega VB, Thomsen JS, Zhang T, Kong SL, Xie M, Chiu KP, Lipovich L, Barnett DH, Stossi F, Yeo A, George J, Kuznetsov VA, Lee YK, Charn TH, Palanisamy N, Miller LD, Cheung E, Katzenellenbogen BS, Ruan Y, Bourque G, Wei CL, Liu ET "Whole-genome cartography of estrogen receptor alpha binding sites.." PLoS Genet.. 2007 June ; 3 (6): e87. Pubmed PMID: 17542648
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