Kendal
Middle Name
D
Hirschi, Ph.D.
Middle Name
D
Picture

Positions
- Professor
-
Pediatrics-Nutrition
Baylor College of Medicine
Houston, TX US
- Professor
-
Molecular and Human Genetics
Baylor College of Medicine
- Professor
-
Program in Integrative Molecular and Biomedical Sciences
Baylor College of Medicine
- Professor
-
USDA/ARS Children's Nutrition Research Center
Baylor College of Medicine
- Associate Director of Research
-
Vegetables and Fruit Improvement Center
Texas AandM University
Education
- BS from University Of Arizona
- 01/1984 - Tucson, AZ United States
- MS from Arizona State University
- 01/1988 - Tempe, AZ United States
- PhD from University Of Arizona
- 01/1993 - Tucson, AZ United States
- Post-Doctoral Fellowship at Whitehead Institute for Biomedical Research
- 01/1993 - Cambridge, Massachusetts United States
Professional Interests
- Nutritional improvement of agriculturally important crops
Professional Statement
We study both model systems biology in plants as well as translational research related to agricultural improvement. At the molecular level, our goals are to understand the structure, biological function, and regulation of transporter proteins that control trafficking into and out of the plant vacuole. Many of our molecular approaches use the standard genetic “tool kit”.Another major goal in our group is to learn how to manipulate the expression and function of these transporters to increase the nutritional content of crop plants, improve plant productivity, and cleanse polluted soils. For this second objective, we collaborate with clinical researchers at the Children's Nutrition Research here at Baylor and faculty at the Vegetable and Fruit Improvement Center at Texas AandM. Obtaining help from nutritional scientists, we perform clinical trials addressing how changes in plant architecture alter nutrient bioavailability.
Websites
Selected Publications
- Yang J, Elbaz-Younes I, Primo C, Murungi D, Hirschi KD "Intestinal permeability, digestive stability and oral bioavailability of dietary small RNAs." Sci Rep. 2018 : Pubmed PMID: 29980707
- "The atypical genesis and bioavailability of the plant‐based small RNA MIR2911: Bulking up while breaking down." : Pubmed PMID: 28319645
- "Heterodimerization of Arabidopsis calcium/proton exchangers contributes to regulation of guard cell dynamics and plant defense responses." : Pubmed PMID: 28645169
- "CAX-ing a wide net: Cation/H+ transporters in metal remediation and abiotic stress signaling." : Pubmed PMID: 27061644
- Yarmarkovich M, Hirschi KD "Digesting dietary miRNA therapeutics." Oncotarget. 2015 June ; 6 : 13848-9. Pubmed PMID: 26116837
- "Anomalous uptake and circulatory characteristics of the plant-based small RNA MIR2911." : Pubmed PMID: 27251858
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