Kendal
Middle Name
D
Hirschi, Ph.D.
Middle Name
D
Picture
Positions
- Professor
-
Pediatrics-Nutrition
Baylor College of Medicine
Houston, TX US
Education
- PhD from University Of Arizona
- 01/1993 - Tucson, AZ United States
- Post-Doctoral Fellowship at Whitehead Institute for Biomedical Research
- 01/1993 - Cambridge, Massachusetts United States
Professional Interests
- Nutritional improvement of agriculturally important crops
Websites
Selected Publications
- Spinler JK, Oezguen N, Runge JK, Luna R, Karri V, Yang, Hirschi KD "Dietary impact of a plant-derived microRNR on the gut microbiome." ExRNA. 2020 August ; 2 (11): 2-11. Pubmed PMID: 33542959
- McNeill EM, Hirschi KD "Roles of Regulatory RNAs in Nutritional Control." Ann Rev Nutr. 2020 September ; 40 : 77-104. Pubmed PMID: 32966184
- Hirschi KD "Genetically modified plants: Nutritious sustainable yet underrated." J Nutr. 2020 October ; 150 (10): 2628-2634. Pubmed PMID: 32725215
- Primo C, Pizzio GA, Yang J, Gaxiola RA, Scholz‐Starke J, Hirschi KD "Plant proton pumping pyrophosphatase: the potential for its pyrophosphate synthesis activity to modulate plant growth." Plant Biol. 2019 November ; 22 (6): 989-996. Pubmed PMID: 31081197
- Spinler JK, Karri V, Hirschi KD "Planting the Microbiome." Trends Microbiol. 2019 February ; 27 (2): 90-93. Pubmed PMID: 30600139
- "Navigating dietary small RNAs." : Pubmed PMID: 28694876
- "The atypical genesis and bioavailability of the plant‐based small RNA MIR2911: Bulking up while breaking down." : Pubmed PMID: 28319645
- Scholz-Stark J, Primo C, Yang J, Kandel R, Gaxiola RA, Hirschi KD "The flip side of the Arabidopsis type I proton-pumping pyrophosphatase (AVP1): Using a transmembrane H+ gradient to synthesize pyrophosphate." Trends Microbiol. 2019 February ; 294 (4): 1290-1299. Pubmed PMID: 30510138
- Yang J, Elbaz-Younes I, Primo C, Murungi D, Hirschi KD "Intestinal permeability, digestive stability and oral bioavailability of dietary small RNAs." Sci Rep. 2018 : Pubmed PMID: 29980707
- Cheng NH, Zhang W, Chen WQ, Jin J, Cui X, Butte NF, Chan L, Hirschi KD "A mammalian monothiol glutaredoxin, Grx3, is critical for cell cycle progression during embryogenesis.." FEBS J.. 2011 July ; 278 (14): 2525-39. Pubmed PMID: 21575136
- Han JS, Kim CK, Park SH, Hirschi KD, Mok I "Agrobacterium-mediated transformation of bottle gourd (Lagenaria siceraria Standl.).." Plant Cell Rep.. 2005 March ; 23 (41558): 692-8. Pubmed PMID: 15480686
- Shigaki T, Sreevidya C, Hirschi KD "Analysis of the Ca2+ domain in the Arabidopsis H+/Ca2+ antiporters CAX1 and CAX3.." Plant Mol. Biol.. 2002 October ; 50 (3): 475-83. Pubmed PMID: 12369623
- "Anomalous uptake and circulatory characteristics of the plant-based small RNA MIR2911." : Pubmed PMID: 27251858
- "Arabidopsis glutaredoxin S17 contributes to vegetative growth, mineral accumulation, and redox balance during iron deficiency." 2017 : Pubmed PMID: 28674546
- Cheng NH, Liu JZ, Liu X, Wu Q, Thompson SM, Lin J, Chang J, Whitham SA, Park S, Cohen JD, Hirschi KD "Arabidopsis Monothiol Glutaredoxin, AtGRXS17, Is Critical for Temperature-dependent Postembryonic Growth and Development via Modulating Auxin Response.." J. Biol. Chem.. 2011 June 10; 286 (23): 20398-406. Pubmed PMID: 21515673
- Morris J, Tian H, Park S, Sreevidya CS, Ward JM, Hirschi KD "AtCCX3 is an Arabidopsis endomembrane H+ -dependent K+ transporter.." Plant Physiol.. 2008 November ; 148 (3): 1474-86. Pubmed PMID: 18775974
- Undurraga SF, Santos MP, Paez-Valencia J, Yang H, Hepler PK, Facanha AR, Hirschi KD, Gaxiola RA "Arabidopsis sodium dependent and independent phenotypes triggered by H(+)-PPase up-regulation are SOS1 dependent.." Plant Sci.. 2012 February ; 183 : 96-105. Pubmed PMID: 22195582
- Zhao J, Cheng NH, Motes CM, Blancaflor EB, Moore M, Gonzales N, Padmanaban S, Sze H, Ward JM, Hirschi KD "AtCHX13 is a plasma membrane K+ transporter.." Plant Physiol.. 2008 October ; 148 (2): 796-807. Pubmed PMID: 18676662
- Cheng NH, Liu JZ, Brock A, Nelson RS, Hirschi KD "AtGRXcp, an Arabidopsis chloroplastic glutaredoxin, is critical for protection against protein oxidative damage.." J. Biol. Chem.. 2006 September 8; 281 (36): 26280-8. Pubmed PMID: 16829529
- Morris J, Hirschi KD, Yang J "Biofortifying foods: Tripping over high hurdles." Int. J. Biotech. Food Sci.. 2014 2 : 102-116.
- "CAX-ing a wide net: Cation/H+ transporters in metal remediation and abiotic stress signaling." : Pubmed PMID: 27061644
- Hirschi KD, Zhen RG, Cunningham KW, Rea PA, Fink GR "CAX1, an H+/Ca2+ antiporter from Arabidopsis.." Proc. Natl. Acad. Sci. U.S.A.. 1996 August 6; 93 (16): 8782-6. Pubmed PMID: 8710949
- Conn SJ, Gilliham M, Athman A, Schreiber AW, Baumann U, Moller I, Cheng NH, Stancombe MA, Hirschi KD, Webb AA, Burton R, Kaiser BN, Tyerman SD, Leigh RA "Cell-Specific Vacuolar Calcium Storage Mediated by CAX1 Regulates Apoplastic Calcium Concentration, Gas Exchange, and Plant Productivity in Arabidopsis.." Plant Cell. 2011 January ; 23 (1): 240-57. Pubmed PMID: 21258004
- Manohar M, Shigaki T, Mei H, Park S, Marshall J, Aguilar J, Hirschi KD "Characterization of Arabidopsis Ca(2+)/H(+) Exchanger CAX3.." Biochemistry. 2011 July 19; 50 (28): 6189-95. Pubmed PMID: 21657244
- Shigaki T, Hirschi K "Characterization of CAX-like genes in plants: implications for functional diversity.." Gene. 2000 October 31; 257 (2): 291-8. Pubmed PMID: 11080595
- Cheng NH, Pittman JK, Shigaki T, Hirschi KD "Characterization of CAX4, an Arabidopsis H(+)/cation antiporter.." Plant Physiol.. 2002 April ; 128 (4): 1245-54. Pubmed PMID: 11950973
- Cheng NH, Liu JZ, Nelson RS, Hirschi KD "Characterization of CXIP4, a novel Arabidopsis protein that activates the H+/Ca2+ antiporter, CAX1.." FEBS Lett.. 2004 February 13; 559 (41277): 99-106. Pubmed PMID: 14960315
- Shigaki T, Hirschi KD "Chimeric gene construction without reference to restriction sites.." BioTechniques. 2002 April ; 32 (4): 736, 738, 740. Pubmed PMID: 11962592
- Zhao J, Li P, Motes CM, Park S, Hirschi KD "CHX14 is a plasma membrane K-efflux transporter that regulates K(+) redistribution in Arabidopsis thaliana.." Plant Cell Environ. 2015 November ; 38 : 2223-38. Pubmed PMID: 25754420
- Cheng NH, Hirschi KD "Cloning and characterization of CXIP1, a novel PICOT domain-containing Arabidopsis protein that associates with CAX1.." J. Biol. Chem.. 2003 February 21; 278 (8): 6503-9. Pubmed PMID: 12480930
- Punshon T, Tappero R, Ricachenevsky FK, Hirschi K, Nakata PA "Contrasting calcium localization and speciation in leaves of Medicago truncatula mutant COD5 analyzed via synchrotron X-ray techniques." Plant J. 2013 November ; 76 : 627-33. Pubmed PMID: 24033783
- Shigaki T, Kole M, Ward JM, Sze H, Hirschi KD "Cre-loxP recombination vectors for the expression of Riken Arabidopsis full-length cDNAs in plants.." BioTechniques. 2005 September ; 39 (3): 301-2, 304. Pubmed PMID: 16206900
- Yang J, Farmer LM, Agyekum AA, Hirschi KD "Detection of dietary plant-based small RNAs in animals." Cell Res. 2015 April ; 25 : 517-20. Pubmed PMID: 25721324
- Kim KM, Park YH, Kim CK, Hirschi K, Sohn JK "Development of transgenic rice plants overexpressing the Arabidopsis H+/Ca2+ antiporter CAX1 gene.." Plant Cell Rep.. 2005 March ; 23 (41558): 678-82. Pubmed PMID: 15372195
- "Diet-responsive microRNAs are likely exogenous." : Pubmed PMID: 26453700
- Hirschi KD, Pruss GJ, Vance V "Dietary delivery: a new avenue for microRNA therapeutics?." Trends Biotechnol. 2015 August ; 33 (8): 431-2. Pubmed PMID: 26113189
- Yang J, Hirschi KD, Farmer LM "Dietary RNAs: New Stories Regarding Oral Delivery." Nutrients. 2015 April ; 7 : 3184-99. Pubmed PMID: 25942490
- Yarmarkovich M, Hirschi KD "Digesting dietary miRNA therapeutics." Oncotarget. 2015 June ; 6 : 13848-9. Pubmed PMID: 26116837
- Pittman JK, Sreevidya CS, Shigaki T, Ueoka-Nakanishi H, Hirschi KD "Distinct N-terminal regulatory domains of Ca(2+)/H(+) antiporters.." Plant Physiol.. 2002 October ; 130 (2): 1054-62. Pubmed PMID: 12376668
- Shigaki T, Hirschi KD "Diverse functions and molecular properties emerging for CAX cation/H+ exchangers in plants.." Plant Biol (Stuttg). 2006 July ; 8 (4): 419-29. Pubmed PMID: 16906482
- Pittman JK, Hirschi KD "Don't shoot the (second) messenger: endomembrane transporters and binding proteins modulate cytosolic Ca2+ levels.." Curr. Opin. Plant Biol.. 2003 June ; 6 (3): 257-62. Pubmed PMID: 12753975
- Wu Q, Shigaki T, Han JS, Kim CK, Hirschi KD, Park S "Ectopic expression of a maize calreticulin mitigates calcium deficiency-like disorders in sCAX1-expressing tobacco and tomato." Plant Mol Biol. 2012 December ; 80 (6): 609-19. Pubmed PMID: 23007728
- Wu Q, Lin J, Liu JZ, Wang X, Lim W, Oh M, Park J, Rajashekar CB, Whitham SA, Cheng NH, Hirschi KD, Park S "Ectopic expression of Arabidopsis glutaredoxin AtGRXS17 enhances thermotolerance in tomato." Plant Biotechnol J. 2012 October ; 10 (8): 945-55. Pubmed PMID: 22762155
- Brannon PM, Hirschi K, Korc M "Effects of epidermal growth factor, insulin and insulin-like growth factor I on rat pancreatic acinar cells cultured in serum-free medium.." Pancreas. 1988 3 (1): 41-8. Pubmed PMID: 3283731
- Park SH, Morris JL, Park JE, Hirschi KD, Smith RH "Efficient and genotype-independent Agrobacterium--mediated tomato transformation.." J. Plant Physiol.. 2003 October ; 160 (10): 1253-7. Pubmed PMID: 14610894
- Koren'kov V, Park S, Cheng NH, Sreevidya C, Lachmansingh J, Morris J, Hirschi K, Wagner GJ "Enhanced Cd2+ -selective root-tonoplast-transport in tobaccos expressing Arabidopsis cation exchangers.." Planta. 2007 January ; 225 (2): 403-11. Pubmed PMID: 16845524
- Korenkov V, Hirschi K, Crutchfield JD, Wagner GJ "Enhancing tonoplast Cd/H antiport activity increases Cd, Zn, and Mn tolerance, and impacts root/shoot Cd partitioning in Nicotiana tabacum L.." Planta. 2007 November ; 226 (6): 1379-87. Pubmed PMID: 17636324
- Pittman JK, Shigaki T, Hirschi KD "Evidence of differential pH regulation of the Arabidopsis vacuolar Ca2+/H+ antiporters CAX1 and CAX2.." FEBS Lett.. 2005 May 9; 579 (12): 2648-56. Pubmed PMID: 15862304
- Barkla BJ, Hirschi KD, Pittman JK "Exchangers man the pumps: Functional interplay between proton pumps and proton-coupled Ca exchangers.." Plant Signal Behav. 2008 May ; 3 (5): 354-6. Pubmed PMID: 19841670
- Wu Q, Shigaki T, Williams KA, Han JS, Kim CK, Hirschi KD, Park S "Expression of an Arabidopsis Ca(2+)/H(+) antiporter CAX1 variant in petunia enhances cadmium tolerance and accumulation.." J. Plant Physiol.. 2011 January 15; 168 (2): 167-73. Pubmed PMID: 20633955
- Kim CK, Han JS, Lee HS, Oh JY, Shigaki T, Park SH, Hirschi K "Expression of an Arabidopsis CAX2 variant in potato tubers increases calcium levels with no accumulation of manganese.." Plant Cell Rep.. 2006 November ; 25 (11): 1226-32. Pubmed PMID: 17024452
- Hirschi KD "Expression of Arabidopsis CAX1 in tobacco: altered calcium homeostasis and increased stress sensitivity.." Plant Cell. 1999 November ; 11 (11): 2113-22. Pubmed PMID: 10559438
- Hirschi KD, Korenkov VD, Wilganowski NL, Wagner GJ "Expression of arabidopsis CAX2 in tobacco. Altered metal accumulation and increased manganese tolerance.." Plant Physiol.. 2000 September ; 124 (1): 125-33. Pubmed PMID: 10982428
- Hirschi K, VanEtten H "Expression of the pisatin detoxifying genes (PDA) of Nectria haematococca in vitro and in planta.." Mol. Plant Microbe Interact.. 1996 August ; 9 (6): 483-91. Pubmed PMID: 8755624
- Sze H, Padmanaban S, Cellier F, Honys D, Cheng NH, Bock KW, Conéjéro G, Li X, Twell D, Ward JM, Hirschi KD "Expression patterns of a novel AtCHX gene family highlight potential roles in osmotic adjustment and K+ homeostasis in pollen development.." Plant Physiol.. 2004 September ; 136 (1): 2532-47. Pubmed PMID: 15347787
- Pittman JK, Shigaki T, Marshall JL, Morris JL, Cheng NH, Hirschi KD "Functional and regulatory analysis of the Arabidopsis thaliana CAX2 cation transporter.." Plant Mol. Biol.. 2004 December ; 56 (6): 959-71. Pubmed PMID: 15821993
- Cheng NH, Pittman JK, Shigaki T, Lachmansingh J, LeClere S, Lahner B, Salt DE, Hirschi KD "Functional association of Arabidopsis CAX1 and CAX3 is required for normal growth and ion homeostasis.." Plant Physiol.. 2005 August ; 138 (4): 2048-60. Pubmed PMID: 16055687
- Pittman JK, Cheng NH, Shigaki T, Kunta M, Hirschi KD "Functional dependence on calcineurin by variants of the Saccharomyces cerevisiae vacuolar Ca2+/H+ exchanger Vcx1p.." Mol. Microbiol.. 2004 November ; 54 (4): 1104-16. Pubmed PMID: 15522090
- Zhao J, Connorton JM, Guo Y, Li X, Shigaki T, Hirschi KD, Pittman JK "Functional studies of split Arabidopsis Ca2+/H+ exchangers.." J. Biol. Chem.. 2009 December 4; 284 (49): 34075-83. Pubmed PMID: 19819871
- Hirschi KK, Burt JM, Hirschi KD, Dai C "Gap junction communication mediates transforming growth factor-beta activation and endothelial-induced mural cell differentiation.." Circ. Res.. 2003 September 5; 93 (5): 429-37. Pubmed PMID: 12919949
- Park S, Kang TS, Kim CK, Han JS, Kim S, Smith RH, Pike LM, Hirschi KD "Genetic manipulation for enhancing calcium content in potato tuber.." J. Agric. Food Chem.. 2005 July 13; 53 (14): 5598-603. Pubmed PMID: 15998121
- Gaxiola RA, Fink GR, Hirschi KD "Genetic manipulation of vacuolar proton pumps and transporters.." Plant Physiol.. 2002 July ; 129 (3): 967-73. Pubmed PMID: 12114553
- Li X, Yang J, Morris J, Hester A, Nakata PA, Hirschi KD "Genetically modified Medicago truncatula lacking calcium oxalate has increased calcium bioavailability and partially rescues vitamin D receptor knockout mice phenotypes." J Bioequivalence Bioavailability. 2013 5 (1): 047-052.
- "Heterodimerization of Arabidopsis calcium/proton exchangers contributes to regulation of guard cell dynamics and plant defense responses." : Pubmed PMID: 28645169
- Schreier HJ, Rostkowski CA, Nomellini JF, Hirschi KD "Identification of DNA sequences involved in regulating Bacillus subtilis glnRA expression by the nitrogen source.." J. Mol. Biol.. 1991 July 20; 220 (2): 241-53. Pubmed PMID: 1677426
- Shigaki T, Rees I, Nakhleh L, Hirschi KD "Identification of three distinct phylogenetic groups of CAX cation/proton antiporters.." J. Mol. Evol.. 2006 December ; 63 (6): 815-25. Pubmed PMID: 17086450
- Magidin M, Pittman JK, Hirschi KD, Bartel B "ILR2, a novel gene regulating IAA conjugate sensitivity and metal transport in Arabidopsis thaliana.." Plant J.. 2003 August ; 35 (4): 523-34. Pubmed PMID: 12904214
- Mei H, Zhao J, Pittman JK, Lachmansingh J, Park S, Hirschi KD "In planta regulation of the Arabidopsis Ca(2+)/H(+) antiporter CAX1.." J. Exp. Bot.. 2007 58 (12): 3419-27. Pubmed PMID: 17898422
- Morris J, Nakata PA, McConn M, Brock A, Hirschi KD "Increased calcium bioavailability in mice fed genetically engineered plants lacking calcium oxalate.." Plant Mol. Biol.. 2007 July ; 64 (5): 613-8. Pubmed PMID: 17514431
- Park S, Cheng NH, Pittman JK, Yoo KS, Park J, Smith RH, Hirschi KD "Increased calcium levels and prolonged shelf life in tomatoes expressing Arabidopsis H+/Ca2+ transporters.." Plant Physiol.. 2005 November ; 139 (3): 1194-206. Pubmed PMID: 16244156
- Hirschi KD "Insertional mutants: a foundation for assessing gene function.." Trends Plant Sci.. 2003 May ; 8 (5): 205-7. Pubmed PMID: 12758036
- Bock KW, Honys D, Ward JM, Padmanaban S, Nawrocki EP, Hirschi KD, Twell D, Sze H "Integrating membrane transport with male gametophyte development and function through transcriptomics.." Plant Physiol.. 2006 April ; 140 (4): 1151-68. Pubmed PMID: 16607029
- Zhao J, Shigaki T, Mei H, Guo YQ, Cheng NH, Hirschi KD "Interaction between Arabidopsis Ca2+/H+ exchangers CAX1 and CAX3.." J. Biol. Chem.. 2009 February 13; 284 (7): 4605-15. Pubmed PMID: 19098009
- Shigaki T, Pittman JK, Hirschi KD "Manganese specificity determinants in the Arabidopsis metal/H+ antiporter CAX2.." J. Biol. Chem.. 2003 February 21; 278 (8): 6610-7. Pubmed PMID: 12496310
- Pittman JK, Shigaki T, Cheng NH, Hirschi KD "Mechanism of N-terminal autoinhibition in the Arabidopsis Ca(2+)/H(+) antiporter CAX1.." J. Biol. Chem.. 2002 July 19; 277 (29): 26452-9. Pubmed PMID: 12006570
- Hirschi KD, Kreps JA, Hirschi KK "Molecular approaches to studying nutrient metabolism and function: an array of possibilities.." J. Nutr.. 2001 May ; 131 (5): 1605S-9S. Pubmed PMID: 11340125
- "Moving on up: H+-PPase mediated crop improvement.." : Pubmed PMID: 26818803
- Hirschi KD "New foods for thought." Trends Plant Sci. 2012 March ; 17 (3): 123-5. Pubmed PMID: 22265093
- Morris J, Hawthorne KM, Hotze T, Abrams SA, Hirschi KD "Nutritional impact of elevated calcium transport activity in carrots.." Proc. Natl. Acad. Sci. U.S.A.. 2008 February 5; 105 (5): 1431-5. Pubmed PMID: 18202180
- Hirschi K "Nutritional improvements in plants: time to bite on biofortified foods.." Trends Plant Sci.. 2008 September ; 13 (9): 459-63. Pubmed PMID: 18635389
- Kontoyiannis DP, Sagar N, Hirschi KD "Overexpression of Erg11p by the regulatable GAL1 promoter confers fluconazole resistance in Saccharomyces cerevisiae.." Antimicrob. Agents Chemother.. 1999 November ; 43 (11): 2798-800. Pubmed PMID: 10543768
- Hirschi KD, Miranda ML, Wilganowski NL "Phenotypic changes in Arabidopsis caused by expression of a yeast vacuolar Ca2+/H+ antiporter.." Plant Mol. Biol.. 2001 May ; 46 (1): 57-65. Pubmed PMID: 11437250
- "Phylogenetic analysis and protein structure modelling identifies distinct Ca2+/Cation antiporters and conservation of gene family structure within Arabidopsis and rice species.." : Pubmed PMID: 26833031
- Mäser P, Thomine S, Schroeder JI, Ward JM, Hirschi K, Sze H, Talke IN, Amtmann A, Maathuis FJ, Sanders D, Harper JF, Tchieu J, Gribskov M, Persans MW, Salt DE, Kim SA, Guerinot ML "Phylogenetic relationships within cation transporter families of Arabidopsis.." Plant Physiol.. 2001 August ; 126 (4): 1646-67. Pubmed PMID: 11500563
- Yang J, Punshon T, Guerinot ML, Hirschi KD "Plant calcium content: ready to remodel." Nutrients. 2012 August ; 4 (8): 1120-36. Pubmed PMID: 23016135
- Manohar M, Shigaki T, Hirschi KD "Plant cation/H(+) exchangers (CAXs): biological functions and genetic manipulations.." Plant Biol (Stuttg). 2011 July ; 13 (4): 561-9. Pubmed PMID: 21668596
- Ward JM, Hirschi KD, Sze H "Plants pass the salt.." Trends Plant Sci.. 2003 May ; 8 (5): 200-1. Pubmed PMID: 12758034
- Emery L, Whelan S, Hirschi KD, Pittman JK "Protein Phylogenetic Analysis of Ca(2+)/cation Antiporters and Insights into their Evolution in Plants.." Front Plant Sci. 2012 3 : 1. Pubmed PMID: 22645563
- Schreier HJ, Brown SW, Hirschi KD, Nomellini JF, Sonenshein AL "Regulation of Bacillus subtilis glutamine synthetase gene expression by the product of the glnR gene.." J. Mol. Biol.. 1989 November 5; 210 (1): 51-63. Pubmed PMID: 2573733
- Pittman JK, Hirschi KD "Regulation of CAX1, an Arabidopsis Ca(2+)/H+ antiporter. Identification of an N-terminal autoinhibitory domain.." Plant Physiol.. 2001 November ; 127 (3): 1020-9. Pubmed PMID: 11706183
- Mei H, Cheng NH, Zhao J, Park S, Escareno RA, Pittman JK, Hirschi KD "Root development under metal stress in Arabidopsis thaliana requires the H+/cation antiporter CAX4.." New Phytol.. 2009 183 (1): 95-105. Pubmed PMID: 19368667
- Korenkov V, King B, Hirschi K, Wagner GJ "Root-selective expression of AtCAX4 and AtCAX2 results in reduced lamina cadmium in field-grown Nicotiana tabacum L.." Plant Biotechnol. J.. 2009 April ; 7 (3): 219-26. Pubmed PMID: 19175521
- Park S, Elless MP, Park J, Jenkins A, Lim W, Chambers E, Hirschi KD "Sensory analysis of calcium-biofortified lettuce.." Plant Biotechnol. J.. 2009 January ; 7 (1): 106-17. Pubmed PMID: 19021875
- Hirschi KD "Strike while the ionome is hot: making the most of plant genomic advances.." Trends Biotechnol.. 2003 December ; 21 (12): 520-1. Pubmed PMID: 14624858
- Shigaki T, Cheng NH, Pittman JK, Hirschi K "Structural determinants of Ca2+ transport in the Arabidopsis H+/Ca2+ antiporter CAX1.." J. Biol. Chem.. 2001 November 16; 276 (46): 43152-9. Pubmed PMID: 11562366
- Liu X, Liu S, Feng Y, Liu JZ, Chen Y, Pham K, Deng H, Hirschi KD, Wang X, Cheng N "Structural insights into the N-terminal GIY-YIG endonuclease activity of Arabidopsis glutaredoxin AtGRXS16 in chloroplasts." Proc Natl Acad Sci USA. 2013 June 4; 110 (23): 9565-70. Pubmed PMID: 23690600
- Li L, Cheng N, Hirschi KD, Wang X "Structure of Arabidopsis chloroplastic monothiol glutaredoxin AtGRXcp.." Acta Crystallogr. D Biol. Crystallogr.. 2010 June ; 66 : 725-32. Pubmed PMID: 20516625
- Cheng NH, Pittman JK, Barkla BJ, Shigaki T, Hirschi KD "The Arabidopsis cax1 mutant exhibits impaired ion homeostasis, development, and hormonal responses and reveals interplay among vacuolar transporters.." Plant Cell. 2003 February ; 15 (2): 347-64. Pubmed PMID: 12566577
- Zhao J, Barkla BJ, Marshall J, Pittman JK, Hirschi KD "The Arabidopsis cax3 mutants display altered salt tolerance, pH sensitivity and reduced plasma membrane H+-ATPase activity.." Planta. 2008 February ; 227 (3): 659-69. Pubmed PMID: 17968588
- Hirschi KD "The calcium conundrum. Both versatile nutrient and specific signal.." Plant Physiol.. 2004 September ; 136 (1): 2438-42. Pubmed PMID: 15375199
- Shigaki T, Vyzasatya RR, Sivitz AB, Ward JM, Sze H, Hirschi KD "The Cre-loxP recombination-based reporter system for plant transcriptional expression studies.." Plant Mol. Biol.. 2005 May ; 58 (1): 65-73. Pubmed PMID: 16028117
- Shigaki T, Mei H, Marshall J, Li X, Manohar M, Hirschi KD "The expression of the open reading frame of Arabidopsis CAX1, but not its cDNA, confers metal tolerance in yeast.." Plant Biol (Stuttg). 2010 November ; 12 (6): 935-9. Pubmed PMID: 21061745
- Patil BS, Crosby K, Byrne D, Hirschi KD "The intersection of plant breeding, human health and nutritional security: Lessons learned and future perspectives." HortScience. 2014 49 (2): 116-127.
- Punshon T, Hirschi K, Yang J, Lanzirotti A, Lai B, Guerinot ML "The Role of CAX1 and CAX3 in Elemental Distribution and Abundance in Arabidopsis Seed." Plant Physiol. 2012 January ; 158 (1): 352-62. Pubmed PMID: 22086421
- Witwer KW, Hirschi KD "Transfer and functional consequences of dietary microRNAs in vertebrates: Concepts in search of corroboration." BioEssays. 2014 36 (4): 394-406. Pubmed PMID: 24436255
- Cheng NH, Pittman JK, Zhu JK, Hirschi KD "The protein kinase SOS2 activates the Arabidopsis H(+)/Ca(2+) antiporter CAX1 to integrate calcium transport and salt tolerance.." J. Biol. Chem.. 2004 January 23; 279 (4): 2922-6. Pubmed PMID: 14583601
- Park S, Li J, Pittman JK, Berkowitz GA, Yang H, Undurraga S, Morris J, Hirschi KD, Gaxiola RA "Up-regulation of a H+-pyrophosphatase (H+-PPase) as a strategy to engineer drought-resistant crop plants.." Proc. Natl. Acad. Sci. U.S.A.. 2005 December 27; 102 (52): 18830-5. Pubmed PMID: 16361442
- Kendal Hirschi "Uptake of dietary milk microRNAs by adult humans: rules for the game of hide and seek." Journal of Nutrition. 2018 148 : 5-6. Pubmed PMID: 29378059
- Shigaki T, Hirschi KD "Use of class IIS restriction enzymes for site-directed mutagenesis: variations on Phoenix mutagenesis.." Anal. Biochem.. 2001 November 1; 298 (1): 118-20. Pubmed PMID: 11673903
- Cho D, Villiers F, Kroniewicz L, Lee S, Seo YJ, Hirschi KD, Leonhardt N, Kwak JM "Vacuolar CAX1 and CAX3 Influence Auxin Transport in Guard Cells via Regulation of Apoplastic pH." Plant Physiol. 2012 November ; 160 (3): 1293-302. Pubmed PMID: 22932758
- Hirschi K "Vacuolar H+/Ca2+ transport: who's directing the traffic?." Trends Plant Sci.. 2001 March ; 6 (3): 100-4. Pubmed PMID: 11239607
- Manohar M, Mei H, Franklin AJ, Sweet EM, Shigaki T, Riley BB, Macdiarmid CW, Hirschi K "Zebrafish (Danio rerio) endomembrane antiporter similar to a yeast cation/H(+) transporter is required for neural crest development.." Biochemistry. 2010 August 10; 49 (31): 6557-66. Pubmed PMID: 20578725
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