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About the Lab
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The Lloyd lab is focused on the following research areas. Read information on each area.
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RNA Granules and Virus
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By definition, stress granules contain translation initiation factors (eIF3, eIF4E, eIF4G, eIF4A, eIF4B) found in stalled translation initiation complexes (cartoon inset). Bonafide stress granules are formed in PV infected cells from 2-3 hrs post infection (marked with eIF3a and eIF4E), then are rapidly destroyed, leaving only Tia-1 foci devoid of stalled mRNA initiation complexes. These remaining foci are pseudo-stress granules.
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