About the Lab
Credit
The Yong Xu lab is interested in novel neural circuits, neurotransmitters and intra-neuronal signals that are critical for coordinated control of body weight, feeding behavior, and glucose balance.
We generate unique mouse models, using Cre-loxP/Flp-frt strategy, with genes of interest manipulated in specific populations of neurons at the time of choice. We use these models, in combination of the modern chemogenetics/optogenetics, fiber photometry, electrophysiology and neurotracing approaches, to establish the physiological relevance of specific neural networks in the regulation of energy homeostasis, glucose balance and behaviors.
Current Projects
- Neural circuits and obesity mechanisms - USDA/CRIS 3092-51000-064-01S
- Neurobiology for the sex differences in energy balance - R01 DK117281
- Brain steroid receptor coactivators and energy homeostasis - P01 DK113954
- Hypothalamic Grb10 and body weight - R01 DK115761
- 5-HT neurons integrate neural inputs to regulate food intake - R01 DK120858
- Brain estrogen regulates energy and glucose balance - R01 DK125480
Researchers identify neurons that regulate blood sugar
Researchers led by Dr. Yong Xu have identified a group of unique glucose-sensing neurons in the brain and how they work together to prevent severe hypoglycemia in mice.
Baylor recognizes research excellence with DeBakey Awards
Dr. Yong Xu was honored, along with other Baylor College of Medicine faculty, through the annual Michael E. DeBakey M.D. Award for Excellence in Research.
USDA/ARS Children's Nutrition Research Center
The CNRC houses laboratories, state-of-the-art equipment, a greenhouse, observation labs and research volunteer accommodations, a metabolic kitchen, and an elite group of scientists conducting groundbreaking research.
Lab Address: 1100 Bates St, #8066, Houston, TX 77030
Contact: Phone 713–798–7199 / Fax 713–798–7199 / Email Yongx@bcm.edu
