Currently we have three main research areas and multiple projects within each area that are open for intelligent and inquisitive trainees to take on. The main research areas can be divided based on model organism used.
Human iNeurons Models
This arm of the lab is in the earliest stages as we are testing and modifying published protocols on deriving motor neurons from human fibroblast samples. Dr. Orengo has access to a bounty of patients with rare genetic variants leading to or associated with motor neuron degeneration through his involvement in the BCM ALS clinic, his rare genetic variant Neuromuscular clinic and his role as a co investigator in the Undiagnosed Diseases Network.