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Joshua Wythe Lab



For a complete listing visit the PubMed link.

Fish JE, Wythe JD. The Molecular Regulation of Arteriovenous Specification and Maintenance. Dev Dyn. 2015 Jan 14. doi: 10.1002/dvdy.24252. [Epub ahead of print] PubMed PMID: 25641373.

Liu Q, Hu T, He L, Huang X, Tian X, Zhang H, He L, Pu W, Zhang L, Sun H, Fang J, Yu Y, Duan S, Hu C, Hui L, Zhang H, Quertermous T, Xu Q, Red-Horse K, Wythe JD, Zhou B. Genetic targeting of sprouting angiogenesis using Apln-CreER. Nat Commun. 2015 Jan 19;6:6020. doi: 10.1038/ncomms7020. PubMed PMID: 25597280; PubMed Central PMCID: PMC4309445.

Devine WP, Wythe JD, George M, Koshiba-Takeuchi K, Bruneau BG. Early patterning and specification of cardiac progenitors in gastrulating mesoderm. Elife. 2014 Oct 8;3. doi: 10.7554/eLife.03848. PubMed PMID: 25296024.

He L, Tian X, Zhang H, Wythe JD, Zhou B. Fabp4-CreER lineage tracing reveals two distinctive coronary vascular populations. J Cell Mol Med. 2014 Sep 30. doi: 10.1111/jcmm.12415. [Epub ahead of print] PMID: 25265869

Wythe JD, Dang LT, Devine WP, Boudreau E, Artap ST, He D, Schachterle W, Stainier DY, Oettgen P, Black BL, Bruneau BG, Fish JE. ETS factors regulate Vegf-dependent arterial specification. Dev Cell. 2013 Jul 15;26(1):45-58. doi: 10.1016/j.devcel.2013.06.007. Epub 2013 Jul 3. PMID: 23830865

Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, Winlaw D, Harvey RP, Fatkin D, Towbin JA, Molkentin JD, Srivastava D, Ocorr K, Bruneau BG, Bodmer R. Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J Cell Biol. 2011 Jun 27;193(7):1181-96. doi: 10.1083/jcb.201006114. Epub 2011 Jun 20. PMID: 21690310

Wythe JD, Jurynec MJ, Urness LD, Jones CA, Sabeh MK, Werdich AA, Sato M, Yost HJ, Grunwald DJ, Macrae CA, Li DY. Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish. Dis Model Mech. 2011 Sep;4(5):607-21. doi: 10.1242/dmm.002204. Epub 2011 May 31. PMID: 21628396

Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DY, Srivastava D, Woo S. A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development. 2011 Apr;138(7):1409-19. doi: 10.1242/dev.060046. PMID: 21385766

Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D. miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell. 2008 Aug;15(2):272-84. doi: 10.1016/j.devcel.2008.07.008. PMID: 18694566

Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY. Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability. Nat Med. 2008 Apr;14(4):448-53. doi: 10.1038/nm1742. Epub 2008 Mar 16. Erratum in: Nat Med. 2008 May;14(5):585. PMID: 18345009

Navankasattusas S, Whitehead KJ, Suli A, Sorensen LK, Lim AH, Zhao J, Park KW, Wythe JD, Thomas KR, Chien CB, Li DY. The netrin receptor UNC5B promotes angiogenesis in specific vascular beds. Development. 2008 Feb;135(4):659-67. doi: 10.1242/dev.013623. PMID: 18223200

Park KW, Urness LD, Senchuk MM, Colvin CJ, Wythe JD, Chien CB, Li DY. Identification of new netrin family members in zebrafish: developmental expression of netrin 2 and netrin 4. Dev Dyn. 2005 Nov;234(3):726-31. PMID: 15973704

Karnik SK, Wythe JD, Sorensen L, Brooke BS, Urness LD, Li DY. Elastin induces myofibrillogenesis via a specific domain, VGVAPG. Matrix Biol. 2003 Sep;22(5):409-25. PMID: 14614988

Karnik SK, Brooke BS, Bayes-Genis A, Sorensen L, Wythe JD, Schwartz RS, Keating MT, Li DY. A critical role for elastin signaling in vascular morphogenesis and disease. Development. 2003 Jan;130(2):411-23. PMID: 12466207