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Martin Matzuk Lab

Publications

Master
Content

Niedenberger BA, Cook K, Baena V, Serra ND, Velte EK, Agno JE, Litwa KA, Terasaki M, Hermann BP, Matzuk MM, Geyer CB. Dynamic cytoplasmic projections connect mammalian spermatogonia in vivo. Development. 2018 Aug 13;145(15). pii: dev161323. doi: 10.1242/dev.161323. PubMed PMID: 29980567.

Yeung TL, Sheng J, Leung CS, Li F, Kim J, Ho SY, Matzuk MM, Lu KH, Wong STC, Mok SC. Systematic Identification of Druggable Epithelial-Stromal Crosstalk Signaling Networks in Ovarian Cancer. J Natl Cancer Inst. 2018 May 31. doi: 10.1093/jnci/djy097. [Epub ahead of print] PubMed PMID: 29860390.

Castaneda JM, Hua R, Miyata H, Oji A, Guo Y, Cheng Y, Zhou T, Guo X, Cui Y, Shen B, Wang Z, Hu Z, Zhou Z, Sha J, Prunskaite-Hyyrylainen R, Yu Z, Ramirez-Solis R, Ikawa M, Matzuk MM, Liu M. TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):E5370-E5378. doi: 10.1073/pnas.1621279114. Epub 2017 Jun 19. PubMed PMID: 28630322; PubMed Central PMCID: PMC5502601.

Jung D, Xiong J, Ye M, Qin X, Li L, Cheng S, Luo M, Peng J, Dong J, Tang F, Shen W, Matzuk MM, Kee K. In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells. Nat Commun. 2017 Jun 12;8:15680. doi: 10.1038/ncomms15680. PubMed PMID: 28604658; PubMed Central PMCID: PMC5472783.

Ogushi S, Yamagata K, Obuse C, Furuta K, Wakayama T, Matzuk MM, Saitou M. Reconstitution of the oocyte nucleolus in mice through a single nucleolar protein, NPM2. J Cell Sci. 2017 Jul 15;130(14):2416-2429. doi: 10.1242/jcs.195875. Epub 2017 Jun 9. PubMed PMID: 28600324.

Fullerton PT Jr, Monsivais D, Kommagani R, Matzuk MM. Follistatin is critical for mouse uterine receptivity and decidualization. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4772-E4781. doi: 10.1073/pnas.1620903114. Epub 2017 May 30. PubMed PMID: 28559342; PubMed Central PMCID: PMC5474784.

Monsivais D, Clementi C, Peng J, Fullerton PT Jr, Prunskaite-Hyyryläinen R, Vainio SJ, Matzuk MM. BMP7 Induces Uterine Receptivity and Blastocyst Attachment. Endocrinology. 2017 Apr 1;158(4):979-992. doi: 10.1210/en.2016-1629. PubMed PMID: 28324064; PubMed Central PMCID: PMC5460793.

Iwamori T, Iwamori N, Matsumoto M, Ono E, Matzuk MM. Identification of KIAA1210 as a novel X-chromosome-linked protein that localizes to the acrosome and associates with the ectoplasmic specialization in testes. Biol Reprod. 2017 Feb 1;96(2):469-477. doi: 10.1095/biolreprod.116.145458. PubMed PMID: 28203736; PubMed Central PMCID: PMC5819839.

Monsivais D, Matzuk MM, Pangas SA. The TGF-β Family in the Reproductive Tract. Cold Spring Harb Perspect Biol. 2017 Oct 3;9(10). pii: a022251. doi: 10.1101/cshperspect.a022251. Review. PubMed PMID: 28193725; PubMed Central PMCID: PMC5554737.

Hua Y, Choi PW, Trachtenberg AJ, Ng AC, Kuo WP, Ng SK, Dinulescu DM, Matzuk MM, Berkowitz RS, Ng SW. Epithelialization of mouse ovarian tumor cells originating in the fallopian tube stroma. Oncotarget. 2016 Oct 4;7(40):66077-66086. doi: 10.18632/oncotarget.11808. PubMed PMID: 27602775; PubMed Central PMCID: PMC5323216.

Iwamori N, Tominaga K, Sato T, Riehle K, Iwamori T, Ohkawa Y, Coarfa C, Ono E, Matzuk MM. MRG15 is required for pre-mRNA splicing and spermatogenesis. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5408-15. doi: 10.1073/pnas.1611995113. Epub 2016 Aug 29. PubMed PMID: 27573846; PubMed Central PMCID: PMC5027415.

Balhara J, Shan L, Zhang J, Muhuri A, Halayko AJ, Almiski MS, Doeing D, McConville J, Matzuk MM, Gounni AS. Pentraxin 3 deletion aggravates allergic inflammation through a T(H)17-dominant phenotype and enhanced CD4 T-cell survival. J Allergy Clin Immunol. 2017 Mar;139(3):950-963.e9. doi: 10.1016/j.jaci.2016.04.063. Epub 2016 Jul 26. PubMed PMID: 27567326.

Miyata H, Castaneda JM, Fujihara Y, Yu Z, Archambeault DR, Isotani A, Kiyozumi D, Kriseman ML, Mashiko D, Matsumura T, Matzuk RM, Mori M, Noda T, Oji A, Okabe M, Prunskaite-Hyyrylainen R, Ramirez-Solis R, Satouh Y, Zhang Q, Ikawa M, Matzuk MM. Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10. doi: 10.1073/pnas.1608458113. Epub 2016 Jun 29. PubMed PMID: 27357688; PubMed Central PMCID: PMC4948324.

Paine MR, Kim J, Bennett RV, Parry RM, Gaul DA, Wang MD, Matzuk MM, Fernández Whole Reproductive System Non-Negative Matrix Factorization Mass Spectrometry Imaging of an Early-Stage Ovarian Cancer Mouse Model. PLoS One. 2016 May 9;11(5):e0154837. doi: 10.1371/journal.pone.0154837. eCollection 2016. PubMed PMID: 27159635; PubMed Central PMCID: PMC4861325.

Monsivais D, Clementi C, Peng J, Titus MM, Barrish JP, Creighton CJ, Lydon JP, DeMayo FJ, Matzuk MM. Uterine ALK3 is essential during the window of implantation. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):E387-95. doi: 10.1073/pnas.1523758113. Epub 2015 Dec 31. PubMed PMID: 26721398; PubMed Central PMCID: PMC4725477.

Castaneda J, Matzuk MM. DEVELOPMENTAL BIOLOGY. Toward a rapid and reversible male pill. Science. 2015 Oct 23;350(6259):385-6. doi: 10.1126/science.aad4425. pub 2015 Oct 22. PubMed PMID: 26494747.

Peng J, Fullerton PT Jr, Monsivais D, Clementi C, Su GH, Matzuk MM. Uterine Activin-Like Kinase 4 Regulates Trophoblast Development During Mouse Placentation. Mol Endocrinol. 2015 Dec;29(12):1684-93. doi: 10.1210/me.2015-1048. Epub 2015 Oct 20. PubMed PMID: 26484579; PubMed Central PMCID: PMC4664232.

Peng J, Monsivais D, You R, Zhong H, Pangas SA, Matzuk MM. Uterine activin receptor-like kinase 5 is crucial for blastocyst implantation and placental development. Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):E5098-107. doi: 10.1073/pnas.1514498112. Epub 2015 Aug 24. PubMed PMID: 26305969; PubMed Central PMCID: PMC4568667.

Fullerton PT Jr, Creighton CJ, Matzuk MM. Insights Into SMAD4 Loss in Pancreatic Cancer From Inducible Restoration of TGF-β Signaling. Mol Endocrinol. 2015 Oct;29(10):1440-53. doi: 10.1210/me.2015-1102. Epub 2015 Aug 18. PubMed PMID: 26284758; PubMed Central PMCID: PMC4588735.

Chen J, Wang Y, McMonechy MK, Anglesio MS, Yang W, Senz J, Maines-Bandiera S, Rosner J, Trigo-Gonzalez G, Grace Cheng SW, Kim J, Matzuk MM, Morin GB, Huntsman Recurrent DICER1 hotspot mutations in endometrial tumours and their impact on microRNA biogenesis. J Pathol. 2015 Oct;237(2):215-25. doi: 10.1002/path.4569. Epub 2015 Jul 6. PubMed PMID: 26033159.

Liu C, Peng J, Matzuk MM, Yao HH. Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells. Nat Commun. 2015 Apr 28;6:6934. doi: 10.1038/ncomms7934. PubMed PMID: 25917826; PubMed Central PMCID: PMC4413950.

Kim J, Coffey DM, Ma L, Matzuk MM. The ovary is an alternative site of origin for high-grade serous ovarian cancer in mice. Endocrinology. 2015 Jun;156(6):1975-81. doi: 10.1210/en.2014-1977. Epub 2015 Mar 27. PubMed PMID: 25815421; PubMed Central PMCID: PMC5393339.

Kannan K, Coarfa C, Chao PW, Luo L, Wang Y, Brinegar AE, Hawkins SM, Milosavljevic A, Matzuk MM, Yen L. Recurrent BCAM-AKT2 fusion gene leads to a constitutively activated AKT2 fusion kinase in high-grade serous ovarian carcinoma. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1272-7. doi: 10.1073/pnas.1501735112. Epub 2015 Mar 2. PubMed PMID: 25733895; PubMed Central PMCID: PMC4371965.

Yu Z, Kim J, He L, Creighton CJ, Gunaratne PH, Hawkins SM, Matzuk MM. Functional analysis of miR-34c as a putative tumor suppressor in high-grade serous ovarian cancer. Biol Reprod. 2014 Nov;91(5):113. doi: 10.1095/biolreprod.114.121988. Epub 2014 Oct 1. PubMed PMID: 25273528.

Peng J, Wigglesworth K, Rangarajan A, Eppig JJ, Thompson TB, Matzuk MM. Amino acid 72 of mouse and human GDF9 mature domain is responsible for altered homodimer bioactivities but has subtle effects on GDF9:BMP15 heterodimer activities. Biol Reprod. 2014 Dec;91(6):142. doi: 10.1095/biolreprod.114.123158. Epub 2014 Sep 24. PubMed PMID: 25253739; PubMed Central PMCID: PMC4434983.

Park DH, Hong SJ, Salinas RD, Liu SJ, Sun SW, Sgualdino J, Testa G, Matzuk MM, Iwamori N, Lim DA. Activation of neuronal gene expression by the JMJD3 demethylase is required for postnatal and adult brain neurogenesis. Cell Rep. 2014 Sep 11;8(5):1290-9. doi: 10.1016/j.celrep.2014.07.060. Epub 2014 Aug 28. PubMed PMID: 25176653; PubMed Central PMCID: PMC4201382.

Archambeault DR, Matzuk MM. Disrupting the male germ line to find infertility and contraception targets. Ann Endocrinol (Paris). 2014 May;75(2):101-8. doi: 10.1016/j.ando.2014.04.006. Epub 2014 Apr 30. Review. PubMed PMID: 24793995.

Kannan K, Coarfa C, Rajapakshe K, Hawkins SM, Matzuk MM, Milosavljevic A, Yen CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma. PLoS Genet. 2014 Mar 27;10(3):e1004216. doi: 10.1371/journal.pgen.1004216. eCollection 2014 Mar. PubMed PMID: 24675677; PubMed Central PMCID: PMC3967933.

Clementi C, Tripurani SK, Large MJ, Edson MA, Creighton CJ, Hawkins SM, Kovanci E, Kaartinen V, Lydon JP, Pangas SA, DeMayo FJ, Matzuk MM. Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans. PLoS Genet. 2013 Nov;9(11):e1003863. doi: 10.1371/journal.pgen.1003863. Epub 2013 Nov 14. PubMed PMID: 24244176; PubMed Central PMCID: PMC3828128.

Iwamori N, Iwamori T, Matzuk MM. H3K27 demethylase, JMJD3, regulates fragmentation of spermatogonial cysts. PLoS One. 2013 Aug 15;8(8):e72689. doi: 10.1371/journal.pone.0072689. eCollection 2013. PubMed PMID: 23967333; PubMed Central PMCID: PMC3744460.

Nagashima T, Li Q, Clementi C, Lydon JP, DeMayo FJ, Matzuk MM. BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest. 2013 Jun;123(6):2539-50. doi: 10.1172/JCI65710. Epub 2013 May 8. PubMed PMID: 23676498; PubMed Central PMCID: PMC3668851.

Peng J, Li Q, Wigglesworth K, Rangarajan A, Kattamuri C, Peterson RT, Eppig JJ, Thompson TB, Matzuk MM. Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E776-85. doi: 10.1073/pnas.1218020110. Epub 2013 Feb 4. PubMed PMID: 23382188; PubMed Central PMCID: PMC3581982.

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