2021 CTRID Publications


Agrawal R, Ajami NJ, Malhotra S, Chen L, White DL, Sharafkhaneh A, Hoffman KL, Graham DY, El-Serag HB, Petrosino JF, Jiao L. Habitual Sleep Duration and the Colonic Mucosa-Associated Gut Microbiota in Humans-A Pilot Study. Clocks Sleep. 2021 Jul 1;3(3):387-397. doi: 10.3390/clockssleep3030025. PMID: 34287254; PMCID: PMC8293063.

Altman MC, Rinchai D, Baldwin N, Toufiq M, Whalen E, Garand M, Syed Ahamed Kabeer B, Alfaki M, Presnell SR, Khaenam P, Ayllón-Benítez A, Mougin F, Thébault P, Chiche L, Jourde-Chiche N, Phillips JT, Klintmalm G, O'Garra A, Berry M, Bloom C, Wilkinson RJ, Graham CM, Lipman M, Lertmemongkolchai G, Bedognetti D, Thiebaut R, Kheradmand F, Mejias A, Ramilo O, Palucka K, Pascual V, Banchereau J, Chaussabel D. Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data. Nat Commun. 2021 Jul 19;12(1):4385. doi: 10.1038/s41467-021-24584-w. PMID: 34282143; PMCID: PMC8289976.

Barnouin Y, Armamento-Villareal R, Celli A, Jiang B, Paudyal A, Nambi V, Bryant MS, Marcelli M, Garcia JM, Qualls C, Villareal DT. Testosterone Replacement Therapy Added to Intensive Lifestyle Intervention in Older Men With Obesity and Hypogonadism. J Clin Endocrinol Metab. 2021 Mar 8;106(3):e1096-e1110. doi: 10.1210/clinem/dgaa917. PMID: 33351921.

Bashir DA, Da QPradhan SSekhar NValladolid CLam F, Guffey D, Goldman J, Desai MS, Cruz MA, Allen C, Nguyen TCVijayan KV. Secretion of von Willebrand Factor and Suppression of ADAMTS-13 Activity by Markedly High Concentration of Ferritin. Clin Appl Thromb Hemost. 2021 Jan-Dec;27:1076029621992128. doi: 10.1177/1076029621992128. PMID: 33539188; PMCID: PMC7868463.

Biggerstaff KS, White DL, Frankfort BJ, Richardson P, Orengo-Nania S, Garcia J, Chiao EY, Kramer JR. Gout and open-angle glaucoma risk in a veteran population. Graefes Arch Clin Exp Ophthalmol. 2021 Nov;259(11):3371-3379. doi: 10.1007/s00417-021-05273-2. Epub 2021 Jul 17. PMID: 34272610.

Brubaker L, Luu S, Hoffman K, Wood A, Navarro Cagigas M, Yao Q, Petrosino J, Fisher W, Van Buren G. Microbiome changes associated with acute and chronic pancreatitis: A systematic review. Pancreatology. 2021 Jan;21(1):1-14. doi: 10.1016/j.pan.2020.12.013. Epub 2020 Dec 23. PMID: 33376062; PMCID: PMC7869754.

Chandrakantan A, Adler AC, Tohsun M, Kheradamand F, Ray RS, Roth S. Intermittent Hypoxia and Effects on Early Learning/Memory: Exploring the Hippocampal Cellular Effects of Pediatric Obstructive Sleep Apnea. Anesth Analg. 2021 Jul 1;133(1):93-103. doi: 10.1213/ANE.0000000000005273. PMID: 33234943; PMCID: PMC8134503.

Chen F, Zhang Y, Sucgang R, Ramani S, Corry DKheradmand F, Creighton CJ. Meta-analysis of host transcriptional responses to SARS-CoV-2 infection reveals their manifestation in human tumors. Sci Rep. 2021 Jan 28;11(1):2459. doi: 10.1038/s41598-021-82221-4. PMID: 33510359; PMCID: PMC7844278.

Colleluori GVillareal DT. Aging, obesity, sarcopenia and the effect of diet and exercise intervention. Exp Gerontol. 2021 Nov;155:111561. doi: 10.1016/j.exger.2021.111561. Epub 2021 Sep 23. PMID: 34562568.

Colleluori G, Aguirre L, Napoli N, Qualls C, Villareal DTArmamento-Villareal R. Testosterone Therapy Effects on Bone Mass and Turnover in Hypogonadal Men with Type 2 Diabetes. J Clin Endocrinol Metab. 2021 Jul 13;106(8):e3058-e3068. doi: 10.1210/clinem/dgab181. PMID: 33735389.

Courson JA, Landry PT, Do T, Spehlmann E, Lafontant PJ, Patel N, Rumbaut RE, Burns AR. Serial Block-Face Scanning Electron Microscopy (SBF-SEM) of Biological Tissue Samples. J Vis Exp. 2021 Mar 26;(169):10.3791/62045. doi: 10.3791/62045. PMID: 33843931; PMCID: PMC8225236.

De La Cruz A, Hargrave A, Magadi S, Courson JA, Landry PT, Zhang W, Lam FWBray MASmith CW, Burns AR, Rumbaut RE. Platelet and Erythrocyte Extravasation across Inflamed Corneal Venules Depend on CD18, Neutrophils, and Mast Cell Degranulation. Int J Mol Sci. 2021 Jul 8;22(14):7360. doi: 10.3390/ijms22147360. PMID: 34298979; PMCID: PMC8329926.

Fang J, Sun X, Liu S, Yang P, Lin J, Feng J, Cruz MA, Dong JF, Fang Y, Wu J. Shear Stress Accumulation Enhances von Willebrand Factor-Induced Platelet P-Selectin Translocation in a PI3K/Akt Pathway-Dependent Manner. Front Cell Dev Biol. 2021 Jun 1;9:642108. doi: 10.3389/fcell.2021.642108. PMID: 34141704; PMCID: PMC8204100.

Gregori G, Celli A, Barnouin Y, Paudyal A, Armamento-Villareal R, Napoli N, Qualls C, Villareal DT. Cognitive response to testosterone replacement added to intensive lifestyle intervention in older men with obesity and hypogonadism: prespecified secondary analyses of a randomized clinical trial. Am J Clin Nutr. 2021 Nov 8;114(5):1590-1599. doi: 10.1093/ajcn/nqab253. PMID: 34375393; PMCID: PMC8588849.

Hernandez DJ, Alam B, Kemnade JO, Huang AT, Chen AC, Sandulache VC. Consistent multimodality approach to oral cavity and high-risk oropharyngeal cancer in veterans. Am J Otolaryngol. 2021 Nov-Dec;42(6):103166. doi: 10.1016/j.amjoto.2021.103166. Epub 2021 Jul 27. PMID: 34333218.

Hubbard WB, Dong JF, Cruz MARumbaut RE. Links between thrombosis and inflammation in traumatic brain injury. Thromb Res. 2021 Feb;198:62-71. doi: 10.1016/j.thromres.2020.10.041. Epub 2020 Nov 25. PMID: 33290884; PMCID: PMC7867616.

Jiao L, Kourkoumpetis T, Hutchinson D, Ajami NJ, Hoffman K, White DL, Graham DY, Hair C, Shah R, Kanwal F, Jarbrink-Sehgal M, Husain N, Hernaez R, Hou J, Cole R, Velez M, Ketwaroo G, Kramer J, El-Serag HB, Petrosino JF. Spatial Characteristics of Colonic Mucosa-Associated Gut Microbiota in Humans. Microb Ecol. 2021 Jul 5. doi: 10.1007/s00248-021-01789-6. Epub ahead of print. PMID: 34223947.

Jurica JM, Rubio F, Hernandez DJ, Sandulache VC. Institutional financial toxicity of failure to adhere to treatment guidelines for head and neck squamous cell carcinoma. Head Neck. 2021 Mar;43(3):816-824. doi: 10.1002/hed.26539. Epub 2020 Nov 9. PMID: 33166016.

Konduri V, Joseph SK, Byrd TT, Nawas Z, Vazquez-Perez J, Hofferek CJ, Halpert MM, Liu D, Liang Z, Baig Y, Salsman VS, Oyewole-Said D, Tsimelzon A, Burns BA, Chen C, Levitt JM, Yao Q, Ahmed NM, Hegde M, Decker WK. A subset of cytotoxic effector memory T cells enhances CAR T cell efficacy in a model of pancreatic ductal adenocarcinoma. Sci Transl Med. 2021 May 5;13(592):eabc3196. doi: 10.1126/scitranslmed.abc3196. PMID: 33952672.

Li E, Scheurer M, Kheradmand F, Luong AU, Corry DB. Computer-Assisted Analysis of Oral Antifungal Therapy in Chronic Rhinosinusitis with Airway Mycosis: a Retrospective Cohort Analysis. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0169721. doi: 10.1128/AAC.01697-21. Epub 2021 Sep 7. PMID: 34491802; PMCID: PMC8522785.

Li E, Rodriguez A, Luong AU, Allen D, Knight JM, Kheradmand FCorry DB. The immune response to airway mycosis. Curr Opin Microbiol. 2021 Aug;62:45-50. doi: 10.1016/j.mib.2021.04.009. Epub 2021 May 27. PMID: 34052540; PMCID: PMC8286351.

Lichtenberger LM, Vijayan KV. Is COVID-19-Induced Platelet Activation a Cause of Concern for Patients with Cancer? Cancer Res. 2021 Mar 1;81(5):1209-1211. doi: 10.1158/0008-5472.CAN-20-3691. Epub 2020 Dec 21. PMID: 33355186; PMCID: PMC8026656.

Lin H, Scull BP, Goldberg BR, Abhyankar HA, Eckstein OE, Zinn DJ, Lubega J, Agrusa J, El Mallawaney N, Gulati N, Forbes L, Chinn I, Chakraborty R, Velasquez J, Goldman J, Bashir D, Lam F, Muscal E, Henry MM, Greenberg JN, Ladisch S, Hermiston ML, Meyer LK, Jeng M, Naqvi A, McClain K, Nguyen T, Wong H, Man TK, Jordan MB, Allen CE. IFN-γ signature in the plasma proteome distinguishes pediatric hemophagocytic lymphohistiocytosis from sepsis and SIRS. Blood Adv. 2021 Sep 14;5(17):3457-3467. doi: 10.1182/bloodadvances.2021004287. PMID: 34461635; PMCID: PMC8525230.

Lü JM, Liang Z, Liu D, Zhan B, Yao Q, Chen C. Two Antibody-Guided Lactic-co-Glycolic Acid-Polyethylenimine (LGA-PEI) Nanoparticle Delivery Systems for Therapeutic Nucleic Acids. Pharmaceuticals (Basel). 2021 Aug 25;14(9):841. doi: 10.3390/ph14090841. PMID: 34577541; PMCID: PMC8470087.

Oh H, Lee J, Patriquin MA, Oldham J, Salas R. Reward Processing in Psychiatric Inpatients With Depression. Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Jun 24:S2451-9022(21)00172-5. doi: 10.1016/j.bpsc.2021.05.010. Epub ahead of print. PMID: 34174484.

Oh H, Gosnell S, Nguyen T, Tran T, Kosten TR, Salas R. Cingulate Cortex Structural Alterations in Substance Use Disorder Psychiatric Inpatients. Am J Addict. 2021 Jan;30(1):72-79. doi: 10.1111/ajad.13093. Epub 2020 Nov 24. PMID: 33232571.

Pinjari OF, Dasgupta SK, Okusaga OO. Plasma Soluble P-selectin, Interleukin-6 and S100B Protein in Patients with Schizophrenia: a Pilot Study. Psychiatr Q. 2021 Oct 2. doi: 10.1007/s11126-021-09954-3. Epub ahead of print. PMID: 34599734.

Shan Z, Li L, Atkins CL, Wang M, Wen Y, Jeong J, Moreno NF, Feng D, Gui X, Zhang N, Lee CG, Elias JA, Lee WM, Gao B, Lam FW, An Z, Ju C. Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment. Elife. 2021 Jun 10;10:e68571. doi: 10.7554/eLife.68571. PMID: 34110284; PMCID: PMC8233036.

Sheikh-Hamad D. Reply to Bankir: Does a Cori cycle exist in the kidney? Am J Physiol Renal Physiol. 2021 Sep 1;321(3):F355. doi: 10.1152/ajprenal.00301.2021. PMID: 34460353.

Sheikh-Hamad D. Hints for a kidney lactate shuttle and lactomone. Am J Physiol Renal Physiol. 2021 Jun 1;320(6):F1028-F1029. doi: 10.1152/ajprenal.00160.2021. Epub 2021 May 3. PMID: 33938240.

Shen H, Holliday M, Sheikh-Hamad D, Li Q, Tong Q, Hamad CD, Pan JS. Sirtuin-3 mediates sex differences in kidney ischemia-reperfusion injury. Transl Res. 2021 Sep;235:15-31. doi: 10.1016/j.trsl.2021.03.015. Epub 2021 Mar 28. PMID: 33789208.

Song J, Christensen RD, Thiagarajan P, Prchal JT. Does neocytolysis exist after descent from high altitude? Acta Physiol (Oxf). 2021 Nov;233(3):e13713. doi: 10.1111/apha.13713. Epub 2021 Jul 14. PMID: 34228882.

Thiagarajan P, Parker CJ, Prchal JT. How Do Red Blood Cells Die? Front Physiol. 2021 Mar 15;12:655393. doi: 10.3389/fphys.2021.655393. PMID: 33790808; PMCID: PMC8006275.

Tsivgoulis G, Katsanos AH, Mandava P, Köhrmann M, Soinne L, Barreto AD, Sharma VK, Mikulik R, Muir KW, Rothlisberger T, Grotta JC, Levi CR, Molina CA, Saqqur M, Mavridis D, Psaltopoulou T, Vosko MR, Fiebach JB, Sandset EC, Kent TA, Alexandrov AW, Schellinger PD, Alexandrov AV; CLOTBUST-ER Trial Investigators. Blood pressure excursions in acute ischemic stroke patients treated with intravenous thrombolysis. J Hypertens. 2021 Feb 1;39(2):266-272. doi: 10.1097/HJH.0000000000002628. PMID: 32956103.

Veeramachaneni R, Yu W, Newton JM, Kemnade JO, Skinner HD, Sikora AG, Sandulache VC. Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects. J Immunother Cancer. 2021 Jul;9(7):e002773. doi: 10.1136/jitc-2021-002773. PMID: 34230113; PMCID: PMC8261884.

Warren EAK, Anil J, Castro PD, Kemnade J, Suzuki M, Hegde M, Hicks J, Yu W, Sandulache V, Sikora AG. Human epidermal growth factor receptor 2 expression in head and neck squamous cell carcinoma: Variation within and across primary tumor sites, and implications for antigen-specific immunotherapy. Head Neck. 2021 Jul;43(7):1983-1994. doi: 10.1002/hed.26662. Epub 2021 Mar 4. PMID: 33660372.

Waters DL, Aguirre L, Gurney AB, Sinacore DR, Fowler K, Gregori G, Armamento-Villareal R, Qualls C, Villareal DT. Effect of Aerobic or Resistance Exercise, or Both, on Intermuscular and Visceral Fat and Physical and Metabolic Function in Older Adults with Obesity While Dieting. J Gerontol A Biol Sci Med Sci. 2021 Apr 11:glab111. doi: 10.1093/gerona/glab111. Epub ahead of print. PMID: 33839788.

Wu Y, Zeng Z, Guo Y, Song L, Weatherhead JE, Huang X, Zeng Y, Bimler L, Chang CY, Knight JM, Valladolid C, Sun H, Cruz MA, Hube B, Naglik JR, Luong AU, Kheradmand FCorry DB. Candida albicans elicits protective allergic responses via platelet mediated T helper 2 and T helper 17 cell polarization. Immunity. 2021 Nov 9;54(11):2595-2610.e7. doi: 10.1016/j.immuni.2021.08.009. Epub 2021 Sep 9. PMID: 34506733; PMCID: PMC8585696.

Xu AA, Hoffman K, Gurwara S, White DL, Kanwal F, El-Serag HB, Petrosino JF, Jiao L. Oral Health and the Altered Colonic Mucosa-Associated Gut Microbiota. Dig Dis Sci. 2021 Sep;66(9):2981-2991. doi: 10.1007/s10620-020-06612-9. Epub 2020 Sep 24. PMID: 32974807; PMCID: PMC7987909.

Xu X, Wang C, Wu Y, Houck K, Hilton T, Zhou A, Wu X, Han C, Yang M, Yang W, Shi FD, Stolla M, Cruz MA, Li M, Zhang J, Dong JF. Conformation-dependent blockage of activated VWF improves outcomes of traumatic brain injury in mice. Blood. 2021 Jan 28;137(4):544-555. doi: 10.1182/blood.2020007364. PMID: 33507292; PMCID: PMC7845006.

Zeng Y, Zhang Y, Huang X, Song L, Polsky K, Wu Y, Kheradmand F, Guo Y, Green LK, Corry DB, Knight JM. Novel acute hypersensitivity pneumonitis model induced by airway mycosis and high dose lipopolysaccharide. Respir Res. 2021 Oct 10;22(1):263. doi: 10.1186/s12931-021-01850-5. PMID: 34629055; PMCID: PMC8503997.

Zevallos JP, Kramer JR, Sandulache VC, Massa ST, Hartman CM, Mazul AL, Wahle BM, Gerndt SP, Sturgis EM, Chiao EY. National trends in oropharyngeal cancer incidence and survival within the Veterans Affairs Health Care System. Head Neck. 2021 Jan;43(1):108-115. doi: 10.1002/hed.26465. Epub 2020 Sep 12. PMID: 32918302; PMCID: PMC8060873.