Joshua
Middle Name
D.
Wythe, Ph.D.
Middle Name
D.
Picture
Positions
- Assistant Professor
-
Molec.Physiology/CVRI
Baylor College of Medicine
Houston, TX US
Education
- Post-Doctoral Fellowship at University of California, San Francisco
- 01/2014 - San Francisco, California United States
- Cardiovascular Development and Disease
- PhD from University of Utah School of Medicine
- 10/2007 - Salt Lake City, Utah United States
- Oncological Sciences / Cardiovascular Development
- BS from Miami University
- Oxford, Ohio United States
- Botany
- BA from Miami University
- Oxford, Ohio United States
- History
Professional Interests
- Vascular Development
- Cardiac Development
- Transcriptional Regulation of Organogenesis
- Cardiovascular Disease
Websites
Selected Publications
- Lizama CO, Hawkins JS, Schmitt CE, Bos FL, Zape JP, Cautivo KM, Borges Pinto H, Rhyner AM, Yu H, Donohoe ME, Wythe JD, Zovein AC "Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition." Nat Commun. 2015 July ; : Pubmed PMID: 26204127
- Fish JE, Wythe JD "The molecular regulation of arteriovenous specification and maintenance.." Dev Dyn.. 2015 March ; : Pubmed PMID: 25641373
- Liu Q, Hu T, He L, Huang X, Tian X, Zhang H, He L, Pu W, Zhang L, Sun H, Fang J, Yu Y, Duan S, Hu C, Hui L, Zhang H, Quertermous T, Xu Q, Red-Horse K, Wythe JD, Zhou B. "Genetic targeting of sprouting angiogenesis using Apln-CreER." Nat Commun.. 2015 January ; : Pubmed PMID: 25597280
- He L, Tian X, Zhang H, Wythe JD, Zhou B. "Fabp4-CreER lineage tracing reveals two distinctive coronary vascular populations.." J Cell Mol Med. 2014 September ; : Pubmed PMID: 25265869
- Devine WP, Wythe JD, George M, Koshiba-Takeuchi K, Bruneau BG. "Early patterning and specification of cardiac progenitors in gastrulating mesoderm.." Elife. 2014 October ; : Pubmed PMID: 25296024
- Wythe JD, Dang LT, Devine WP, Boudreau E, Artap ST, He D, Schachterle W, Stainier DY, Oettgen P, Black BL, Bruneau BG, Fish JE "ETS factors regulate Vegf-dependent arterial specification." Developmental Cell. 2013 : Pubmed PMID: 23830865
- Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DY, Srivastava D, Woo S "A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish." Development. 2011 : Pubmed PMID: 21385766
- Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN.......Srivastava D, Ocorr K, Bruneau BG, Bodmer R "Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species." J Cell Biol. 2011 : Pubmed PMID: 21690310
- Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D "miR-126 regulates angiogenic signaling and vascular integrity." Dev Cell. : Pubmed PMID: 18694566
- Wythe JD, Jurynec MJ, Urness LD, Jones CA, Sabeh MK, Werdich AA, Sato M, Yost HJ, Grunwald DJ, Macrae CA, Li DY "Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish." Dis Model Mech.. 2011 : Pubmed PMID: 21628396
Memberships
- American Heart Association
- North American Vascular Biology Organization
- Society for Developmental Biology
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