H. Courtney Hodges Lab



Hodges* HC, Stanton* BZ, Cermakova K, Chang CY, Miller EL, Kirkland JG, Ku WL, Veverka V, Zhao K, Crabtree GR. "Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers."Nat Struct Mol Biol. 2018;25(1):61-72. Pubmed PMID: 29323272

Stanton* BZ, Hodges* C, Calarco JP, Braun SM, Ku WL, Kadoch C, Zhao K, Crabtree GR. "Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin."Nat Genet. 2017;49(2):282-288. Pubmed PMID: 27941795

Kadoch C, Hargreaves DC, Hodges C, Elias L, Ho L, Ranish J, Crabtree GR. "Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy."Nat Genet. 2013;45(6):592-601. Pubmed PMID: 23644491

Hodges* C, Bintu* L, Lubkowska L, Kashlev M, Bustamante C. "Nucleosomal fluctuations govern the transcription dynamics of RNA polymerase II."Science. 2009;325(5940):626-628. Pubmed PMID: 19644123

Hathaway NA, Bell O, Hodges C, Miller EL, Neel DS, Crabtree GR. "Dynamics and memory of heterochromatin in living cells."Cell. 2012;149(7):1447-1460. Pubmed PMID: 22704655

Hodges C, Crabtree GR. "Dynamics of inherently bounded histone modification domains."Proc Natl Acad Sci USA. 2012;109(33):13296-13301. Pubmed PMID: 22847427

Hodges C, Kirkland JG, Crabtree GR. "The many roles of BAF (mSWI/SNF) and PBAF complexes in cancer."Cold Spring Harb Perspect Med. 2016;6(8):a026930. Pubmed PMID: 27413115

Wen JD, Lancaster L, Hodges C, Zeri AC, Yoshimura SH, Noller HF, Bustamante C, Tinoco I. "Following translation by single ribosomes one codon at a time."Nature. 2008;452(7187):598-603. Pubmed PMID: 18327250

Sharma S, Cermakova K, De Rijck J, Demeulemeester J, Fabry M, El Ashkar S, Van Belle S, Lepsik M, Tesina P, Duchoslav V, Novak P, Hubalek M, Srb P, Christ F, Rezacova P, Hodges HC, Debyser Z, Veverka V. "Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation."Proc Natl Acad Sci USA. 2018;115(30):E7053-E7062. Pubmed PMID: 29997176

Cermakova K, Hodges HC. "Next-Generation Drugs and Probes for Chromatin Biology: From Targeted Protein Degradation to Phase Separation."Molecules. 2018;23(8):E1958. Pubmed PMID: 30082609

England JP, Hao Y, Bai L, Glick V, Hodges HC, Taylor SS, Maillard RA. "Switching of the folding-energy landscape governs the allosteric activation of protein kinase A."Proc Natl Acad Sci USA. 2018;115(32):E7478-E7485. Pubmed PMID: 30038016