Dr. Orengo serves as a co-investigator in the Undiagnosed Diseases Network (UDN) at Baylor College of Medicine. This NIH funded multi-site collaborative effort is designed to use high level sequencing, transcriptomics metabolomics and animal modeling resources to solve tough cases of undiagnosed individuals with rare diseases. Learn more about the UDN.
All members of the Orengo lab are required to keep an electronic lab notebook via the Benchling interface. Learn more about Benchling.
An integral part of the Orengo lab is integrating a cross species approach towards understanding motor neuron biology and disease: Human, Mouse and Zebrafish. The following links are frequently used by lab members in their day-to-day research and serve as great resources.
Zebrafish International Resource Center
The Zebrafish Information Network (ZFIN) is the database of genetic and genomic data for the zebrafish (Danio rerio) as a model organism. ZFIN provides a wide array of expertly curated, organized and cross-referenced zebrafish research data.
Multiple public variant databases exist where each database is studying a different cohort and providing different types of output. MARRVEL(Model organism Aggregated Resources for Rare Variant ExpLoration) allows users to search multiple public variant databases simultaneously and provides a unified interface to facilitate the search process.
Genome Aggregation Database
The Genome Aggregation Database (gnomAD) is a resource developed by an international coalition of investigators, with the goal of aggregating and harmonizing both exome and genome sequencing data from a wide variety of large-scale sequencing projects, and making summary data available for the wider scientific community.
Search for genes or proteins and their functional terms extracted and organized from over a hundred publicly available resources.
A suite of gene list enrichment analysis tools.
The Allen Institute for Brain Science uses a unique approach to generate data, tools and knowledge for researchers to explore the biological complexity of the mammalian brain. This portal provides access to high quality data and web-based applications created for the benefit of the global research community.
New England BioLabs Tools and Resources
NEB offers several helpful interactive tools for your research and experimental design. In addition, Double Digest Finder and Enzyme Finder are featured on NEBTools, our free app for iPhone® and Android™. You can browse NEB's tools and resources below by resource type, product category or application.