Trent Watkins Lab



Simon DJ, Watkins TA  "Therapeutic opportunities and pitfalls in the treatment of axon degeneration."  Curr Opin Neurol. 2018 December ;31  (6): 693-701. Pubmed PMID: 30320612

Farley MM, Watkins TA  "Intrinsic Neuronal Stress Response Pathways in Injury and Disease."  Annu Rev Pathol. 2018 January 24;  13 : 93-116.Pubmed PMID: 29414247

Larhammar M, Huntwork-Rodriguez S, Jiang Z, Solanoy H, Sengupta Ghosh A, Wang B, Kaminker JS, Huang K, Eastham-Anderson J, Siu M, Modrusan Z, Farley MM, Tessier-Lavigne M, Lewcock JW, Watkins TA"Dual leucine zipper kinase-dependent PERK activation contributes to neuronal degeneration following insult."  Elife. 2017 April 25;  pii :e20725. Pubmed PMID: 28440222

Watkins TA, Scholze AR  "Myelinating cocultures of rat retinal ganglion cell reaggregates and optic nerve oligodendrocyte precursor cells."Cold Spring Harb Protoc. 2014 October 1;  2014  (10): pdb.prot074971.Pubmed PMID: 25275100

Watkins TA, Wang B, Huntwork-Rodriguez S, Yang J, Jiang Z, Eastham-Anderson J, Modrusan Z, Kaminker JS, Tessier-Lavigne M, Lewcock JW"DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury."  Proc Natl Acad Sci U S A. 2013 March 5;  110  (10): 4039-44. Pubmed PMID: 23431164

Huntwork-Rodriguez S, Wang B, Watkins T, Ghosh AS, Pozniak CD, Bustos D, Newton K, Kirkpatrick DS, Lewcock JW  "JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis."  J Cell Biol. 2013 September 2;  202  (5): 747-63.Pubmed PMID: 23979718

Watkins TA, Emery B, Mulinyawe S, Barres BA  "Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system."  Neuron. 2008 November 26;  60  (4):555-69. Pubmed PMID: 19038214

Emery B, Agalliu D, Cahoy JD, Watkins TA, Dugas JC, Mulinyawe SB, Ibrahim A, Ligon KL, Rowitch DH, Barres BA  "Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination."  Cell. 2009 July 10;  138  (1): 172-85. Pubmed PMID: 19596243

Chan JR, Watkins TA, Cosgaya JM, Zhang C, Chen L, Reichardt LF, Shooter EM, Barres BA  "NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes."  Neuron. 2004 July 22;  43  (2):183-91. Pubmed PMID: 15260955