About the Core
The Optical Imaging & Vital Microscopy (OiVM) Core provides state-of-the-art instrumentation and cutting-edge imaging/image analysis tools for the research applications of a broad range of Baylor College of Medicine investigators. This core is dedicated to vital and intravital imaging of cellular processes within cells, intact tissue explants, developing embryos and functioning organs within the live animal. Our users are focused on a variety of applications such as understanding cell migration, optimizing angiogenic therapies, how blood flow influences development and cancer, immune cell recruitment, stem cell-niche interactions and cancer metastasis.
The following microscopy methods are available through the Optical Imaging & Vital Microscopy Core. See information on each below:

Fluorescence Microscopy
Learn more about the cornerstone of our imaging capabilities that can be used with a wide array of sample types.

LightSheet Microscopy
Learn more about how this novel 3D imaging technology can provide more insight into cleared whole mounts.

Confocal Microscopy
Learn more about how our confocal microscopes can improve your fluorescence images.

Multi-Photon Microscopy
Learn more about how our 2-Photon microscopes can help you see deeper into intact tissue.

µCT (Micro Computed Tomography)
Learn more about how μCT technology can generate 3D images from unlabeled samples.

OPT (Optical Projection Tomography)
Learn more about how our custom built OPT solutions provide fast optical sectioning for biological specimens.
Location & Hours
Cullen Building 113A/114A
One Baylor Plaza
Houston, TX 77030
Regular Hours: 8 a.m. to 6 p.m. (Monday - Friday)
Core Approved Users: 24/7
Need Imaging Services?
Visit our Services page to learn more about which service level is right for you.
Want to speak with OiVM Staff about your experiment? Fill out our User Request Form using the button below.
From the Labs
Image of the Month: Trachea and Vasculature of the Mouse Lung
Acknowledgement of Cores in Publications
Core name: Optical Imaging & Vital Microscopy Core
Personnel: Mary E. Dickinson, Ph.D., Academic Director; Jason M. Kirk, Technical Director; Chih-Wei Hsu, Ph.D., Imaging Specialist
Terms & Conditions for Use of Core
View and download the form.